SARC041, abemaciclib for recurrent dedifferentiated liposarcoma

Intervista a Mark A. Dickson By 1 Giugno 2026No Comments
Dai congressi

Abemaciclib, a targeted CDK4/6 inhibitor, is a promising new therapy for advanced dedifferentiated liposarcoma (DDLPS), for which there are few effective treatment options. Results of the phase 3 SARC041 trial – presented at ASCO 2026 congress – show that abemaciclib kept tumors from growing for longer than a placebo in people with DDLPS that recurred after surgery. Abemaciclib was also able to shrink tumors in some participants, a rarity for DDLPS treatments. We discussed the clinical significance of these data in Chicago with Mark A. Dickson, Sarcoma Medical Oncologist at Memorial Sloan Kettering Cancer Center, New York.