Final OS analysis of PATHWAY trial: the clinical significance

Intervista a Yen-Shen Lu By 1 Giugno 2026No Comments
Dai congressi

At ASCO 2026 has been presented the final overall survival (OS) analysis of PATHWAY, an Asian international double-blind randomized phase 3 trial on palbociclib plus tamoxifen ± goserelin in women with hormone receptor (HR)-positive, HER2-negative advanced breast cancer. With longer follow-up, palbociclib plus tamoxifen (± goserelin) provided durable PFS benefit and a favorable OS trend with manageable safety, supporting this regimen as an effective option regardless of menopausal status. We discussed the clinical significance of these data in Chicago with Yen-Shen Lu (National Taiwan University Hospital, Taipei).