An ICI-resistance mechanism associated with MT metabolism

Intervista a Tomas Kirchhoff By 4 Dicembre 2025No Comments
Dai congressi

Response to immune checkpoint inhibitors (ICIs) varies among patients. Mitochondrial (MT) metabolism emerged recently as an important regulator of host immune function: the team of Tomas Kirchhoff (Associate Professor Perlmutter Cancer Center, New York) explored the association of host MT genetics (MT haplogroups) with ICI efficacy, with exciting results. We interviewed Tomas Kirchhoff at the Immunotherapy Bridge 2025 congress in Naples.